Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PER2 | O15055 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846762 | 0.85 | OPRM1 (0.33) | — | |
| SCHEMBL9846735 | 0.84 | IDH1 (0.33) | ADRA1A | |
| SCHEMBL9846701 | 0.84 | ATM (0.33) | SIGMAR1ATMADRA1DADRA1AADRA1B | |
| SCHEMBL9846682 | 0.79 | CASP1 (0.30) | — | |
| SCHEMBL9846748 | 0.79 | TSHR (0.38) | SIGMAR1 | |
| SCHEMBL9846720 | 0.69 | PBRM1 (0.37) | — | |
| SCHEMBL9846695 | 0.65 | BACE1 (0.34) | — | |
| SCHEMBL7783228 | 0.65 | ALDH1A1 (0.34) | ATM | |
| SCHEMBL9846738 | 0.64 | LMNA (0.33) | ADRA1A | |
| SCHEMBL12015718 | 0.63 | MEN1 (0.50) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450487-A1 | Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |