Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 10/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846680 | 0.86 | AGTR1 (0.49) | AGTR1AGTR2NR1H2NR1H3 | |
| SCHEMBL9846769 | 0.79 | NR1H2 (0.48) | NR1H2NR1H3 | |
| SCHEMBL9846756 | 0.75 | NR1H2 (0.48) | NR1H2MAPTRAB9ANR1H3 | |
| SCHEMBL9846714 | 0.74 | AGTR1 (0.47) | AGTR1AGTR2HTTALDH1A1MAPT | |
| SCHEMBL9846759 | 0.69 | AGTR2 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9846782 | 0.68 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL2875418 | 0.67 | NR1H2 (0.51) | NR1H2NR1H3 | |
| SCHEMBL27520457 | 0.65 | AGTR1 (0.80) | AGTR1AGTR2 | |
| SCHEMBL903507 | 0.64 | NR1H2 (0.44) | NR1H2ALDH1A1MAPTRAB9A | |
| SCHEMBL10576800 | 0.64 | AGTR1 (0.60) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |