SCHEMBL9847100

SCHEMBL9847100

CCCCCCCCCCCCCc1ccc2[nH]c(C)nc2c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.43
ADRB2 P07550 1/20 0.38
KCNH2 Q12809 1/20 0.38
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
ALOX5 P09917 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LIPG Q9Y5X9 1/20 0.35
HSD17B10 Q99714 1/20 0.34
CCNB2 O95067 1/20 0.34
CDK1 P06493 1/20 0.34
CCNB1 P14635 1/20 0.34
GSK3A P49840 1/20 0.34
GSK3B P49841 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8016316 0.94 ADRB2 (0.40) TYRADRB2CYP3A4MAPTTSHR
SCHEMBL9847101 0.87 ADRB2 (0.42) ADRB2TSHRHTTHSD17B10PARP1
SCHEMBL10299142 0.80 ADRB2 (0.44) ADRB2HTTTDP1PARP1
SCHEMBL9847103 0.76 TYR (0.43) TYRKCNH2MEN1TP53CYP3A4
SCHEMBL5551551 0.74 ALDH1A1 (0.33) TYRCYP3A4MAPTTSHRHTT
SCHEMBL2330278 0.74 PARP1 (0.47) ADRB2HTTPARP1
SCHEMBL27156172 0.73 ADRB2 (0.48) ADRB2CYP3A4MAPTTSHRHTT
SCHEMBL6753932 0.73 GPR84 (0.42) KMT2AGPR84
SCHEMBL6756142 0.73 GPR84 (0.42) KMT2AGPR84
SCHEMBL6753984 0.73 GPR84 (0.42) KMT2AGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0428260-A2 Metal surface treatment agents SANWA LABORATORY LTD. (JP) 1991-05-22 EP claimed