Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798174 | 0.78 | HPGD (0.59) | FFAR1MAPTHPGDTSHRALDH1A1 | |
| SCHEMBL1004267 | 0.77 | LOXL2 (0.64) | KCNJ1KCNH2LOXL2CYP2A6TSHR | |
| SCHEMBL10452241 | 0.75 | LOXL2 (0.56) | KCNJ1KCNH2LOXL2CYP2A6TSHR | |
| SCHEMBL2513477 | 0.74 | ALDH1A1 (0.52) | MAPTALDH1A1USP2NPSR1ALOX15 | |
| SCHEMBL8381260 | 0.74 | ALDH1A1 (0.52) | MAPTALDH1A1USP2NPSR1ALOX15 | |
| Benzonitrile SCHEMBL8498100 | 0.73 | TSHR (0.45) | FFAR1MAPTHPGDTSHRALDH1A1 | |
| SCHEMBL9351103 | 0.72 | CYP2A6 (0.42) | KCNJ1KCNH2LOXL2CYP2A6TSHR | |
| SCHEMBL8521332 | 0.72 | ALDH1A1 (0.43) | MAPTALDH1A1USP2NPSR1ALOX15 | |
| SCHEMBL250013 | 0.71 | CYP11B2 (0.42) | KCNH2LOXL2CYP2A6TSHRHSD17B10 | |
| SCHEMBL14244155 | 0.71 | SMN1; SMN2 (0.42) | MAPTALDH1A1USP2NPSR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410756-A1 | Cyclohexenylethane compounds | Chisso Corporation (JP) | 1991-01-30 | — | — | EP | disclosed |