Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847873 | 0.89 | HSD11B1 (0.33) | SMN1; SMN2MITFALDH1A1NPC1RAB9A | |
| SCHEMBL9847843 | 0.83 | LMNA (0.38) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL2217683 | 0.72 | SLC6A4 (0.39) | KMT2ASLC6A4 | |
| SCHEMBL22289618 | 0.69 | MITF (0.60) | SMN1; SMN2MITFALDH1A1NPC1RAB9A | |
| SCHEMBL30884762 | 0.68 | ALDH1A1 (0.44) | SMN1; SMN2MITFALDH1A1RAB9AMEN1 | |
| SCHEMBL5176983 | 0.68 | ALDH1A1 (0.44) | SMN1; SMN2MITFALDH1A1RAB9AMEN1 | |
| SCHEMBL20521218 | 0.66 | SLC6A4 (0.36) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL26660405 | 0.66 | ALDH1A1 (0.39) | SMN1; SMN2MITFALDH1A1NPC1RAB9A | |
| SCHEMBL19953554 | 0.65 | ALDH1A1 (0.84) | SMN1; SMN2MITFALDH1A1NPC1RAB9A | |
| SCHEMBL5993915 | 0.64 | ALDH1A1 (0.66) | SMN1; SMN2MITFALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |