Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
| ▸ | PTGIR | P43119 | 2/20 | 0.30 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847824 | 0.89 | SMN1; SMN2 (0.42) | HSD11B1TACR1AKR1B1KDM4EMEN1 | |
| SCHEMBL9847843 | 0.83 | LMNA (0.38) | HSD11B1AKR1B1KDM4EMEN1NPC1 | |
| SCHEMBL9847904 | 0.78 | HSD11B1 (0.40) | HSD11B1TACR1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL2217683 | 0.72 | SLC6A4 (0.39) | KMT2ASLC6A4 | |
| SCHEMBL20521218 | 0.66 | SLC6A4 (0.36) | AKR1B1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL9847821 | 0.64 | KDM4E (0.36) | HSD11B1KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL9847872 | 0.63 | GPR174 (0.37) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9847891 | 0.63 | KDM4E (0.34) | TACR1KDM4EMEN1NPC1MITF | |
| SCHEMBL9847871 | 0.63 | KDM4E (0.35) | HSD11B1KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL9847870 | 0.63 | ALDH1A1 (0.43) | TACR1KDM4EMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |