SCHEMBL9848461

SCHEMBL9848461

CC(C)c1cccc(C(C)C)c1N(CC(CNCc1ccccc1)c1ccccc1)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.40
BACE1 P56817 3/20 0.39
ANPEP P15144 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9848390 0.74
SCHEMBL9723449 0.73 KMT2A (0.43) MEN1KMT2A
SCHEMBL9723469 0.72 LMNA (0.40) MEN1KMT2A
SCHEMBL9848388 0.68
Carbamic Acid SCHEMBL7552207 0.67 ANPEP (0.57) BCHEANPEPMEN1KMT2A
SCHEMBL9723422 0.65 LMNA (0.45) MEN1KMT2A
SCHEMBL8843501 0.65 ANPEP (0.50) BCHEBACE1ANPEPMEN1KMT2A
SCHEMBL9844148 0.64 KMT2A (0.41) MEN1KMT2A
SCHEMBL11081034 0.64 APAF1 (0.54) BCHEANPEPMEN1KMT2A
SCHEMBL13484773 0.64 KMT2A (0.53) BCHEANPEPMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0432442-A1 ACAT inhibitors WARNER-LAMBERT COMPANY (US) 1991-06-19 EP disclosed