Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723469 | 0.83 | LMNA (0.40) | KMT2AMEN1 | |
| SCHEMBL9723422 | 0.78 | LMNA (0.45) | KMT2AMEN1 | |
| SCHEMBL9723522 | 0.76 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5502714 | 0.74 | ALDH1A1 (0.50) | KMT2AMAPTALDH1A1MEN1L3MBTL1 | |
| SCHEMBL9723545 | 0.73 | NPSR1 (0.47) | KMT2AALDH1A1CYP1A2TSHRALOX5 | |
| SCHEMBL9848461 | 0.73 | BCHE (0.40) | KMT2AMEN1 | |
| SCHEMBL9723571 | 0.72 | HSP90AA1 (0.40) | CYP1A2TSHRALOX5SMN1; SMN2 | |
| SCHEMBL27021656 | 0.71 | KMT2A (0.65) | KMT2AMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL11060139 | 0.71 | ALDH1A1 (0.45) | KMT2AALDH1A1MEN1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11562696 | 0.71 | CYP1A2 (0.47) | KMT2AALDH1A1MEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153223-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | claimed |