Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848686 | 0.80 | PPARA (0.47) | KMT2APPARAF2RL1PPARGCYP4F2 | |
| SCHEMBL22499185 | 0.79 | TDP1 (0.58) | KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL23772470 | 0.78 | TDP1 (0.53) | PPARAPPARGCYP4F2CYP4A11MAPT | |
| SCHEMBL10389748 | 0.77 | ALDH1A1 (0.53) | KMT2APPARAF2RL1PPARGMAPT | |
| SCHEMBL2789562 | 0.77 | FFAR1 (0.59) | PPARALMNAL3MBTL1 | |
| SCHEMBL25854966 | 0.75 | LMNA (0.49) | PPARAF2RL1PPARGACACBLMNA | |
| SCHEMBL24001439 | 0.75 | PPARA (0.49) | PPARAF2RL1PPARGACACBLMNA | |
| SCHEMBL7567700 | 0.74 | APP (0.59) | MAPTLMNAALDH1A1HSD17B10 | |
| SCHEMBL18082968 | 0.73 | ADRB2 (0.41) | KMT2AF2RL1CYP4F2CYP4A11MAPT | |
| SCHEMBL24177401 | 0.73 | ELANE (0.52) | KMT2APPARAPPARGCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |