Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.41 |
| ▸ | ATP4B | P51164 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849430 | 0.82 | TSHR (0.50) | TBXAS1CYP19A1QPCT | |
| SCHEMBL439523 | 0.75 | MCHR1 (0.57) | MCHR1 | |
| SCHEMBL9849409 | 0.72 | NOS1 (0.50) | NOS1QPCT | |
| SCHEMBL9849597 | 0.69 | SOD1 (0.48) | CYP19A1QPCT | |
| SCHEMBL10283707 | 0.68 | NOS1 (0.67) | NOS1TBXAS1HMOX1CYP19A1 | |
| Hydrochloric Acid SCHEMBL410883 | 0.67 | NOS1 (0.65) | NOS1TBXAS1HMOX1CYP19A1ATP4A | |
| SCHEMBL437720 | 0.67 | MCHR1 (0.69) | MCHR1 | |
| SCHEMBL1264932 | 0.67 | TBXAS1 (0.60) | NOS1TBXAS1CYP19A1 | |
| SCHEMBL28803051 | 0.66 | CYP19A1 (0.49) | TBXAS1HMOX1CYP19A1 | |
| SCHEMBL3828474 | 0.66 | BACE1 (0.45) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |