Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12910406 | 0.84 | PTPN22 (0.31) | — | |
| SCHEMBL7509409 | 0.84 | CCR1 (0.58) | CCR1RAB9ACCR5METAP2KDM4E | |
| SCHEMBL25233688 | 0.73 | CYP1A2 (0.46) | CCR1RAB9ACCR5METAP2KDM4E | |
| SCHEMBL19001477 | 0.71 | CCR1 (0.44) | CCR1RAB9ACCR5METAP2KDM4E | |
| SCHEMBL22337665 | 0.71 | CRHBP (0.30) | — | |
| SCHEMBL30546638 | 0.71 | NCF1 (0.42) | RAB9AKDM4EALDH1A1CYP1A2KMT2A | |
| SCHEMBL9849288 | 0.71 | CCR1 (0.44) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL3586094 | 0.71 | NCF1 (0.42) | RAB9AKDM4EALDH1A1CYP1A2KMT2A | |
| SCHEMBL2901701 | 0.71 | NOS2 (0.50) | CCR1RAB9ACCR5KDM4ECYP1A2 | |
| SCHEMBL22804140 | 0.70 | ADORA1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169092-A | Transition metal-naphthyridine chemical complexes | BAYER JOHN W | 1979-09-25 | — | — | US | claimed |
| WO-2023176466-A1 | VIRUS DETECTION METHOD | 国立大学法人九州工業大学 | 2023-09-21 | — | — | WO | disclosed |
| CN-105646487-A | Bromo-1,8-naphthyridine derivatives of class and preparation method of bromo-1,8-naphthyridine derivatives of class | 红河学院 | 2016-06-08 | — | — | CN | disclosed |
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4169092-A | Transition metal-naphthyridine chemical complexes | BAYER JOHN W | 1979-09-25 | — | — | US | disclosed |