Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22804124 | 0.76 | ADORA1 (0.58) | ADORA1ADORA2A | |
| SCHEMBL22824545 | 0.74 | BCHE (0.48) | ADORA1ADORA2A | |
| SCHEMBL7509409 | 0.73 | CCR1 (0.58) | — | |
| SCHEMBL19820718 | 0.71 | ADORA1 (0.58) | ADORA1ADORA2A | |
| SCHEMBL9849437 | 0.70 | CCR1 (0.44) | — | |
| SCHEMBL22824496 | 0.69 | MAP4K4 (0.48) | ADORA1 | |
| SCHEMBL22804149 | 0.69 | TRPV3 (0.40) | ADORA1ADORA2A | |
| SCHEMBL22824413 | 0.68 | SMN1; SMN2 (0.57) | ADORA1ADORA2A | |
| SCHEMBL10032538 | 0.67 | CCR1 (0.65) | — | |
| SCHEMBL22804161 | 0.66 | RAB9A (0.53) | ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020253415-A1 | 2-METHYL-1,8-NAPHTHYRIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREFOR | 五邑大学 | 2020-12-24 | — | — | WO | disclosed |