Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 4/20 | 0.43 |
| ▸ | HSPA2 | P54652 | 3/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | CIT | O14578 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.36 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26965355 | 0.84 | FDPS (0.44) | HSPA5HSPA2FDPSCYP3A4FFAR2 | |
| SCHEMBL27127787 | 0.84 | FDPS (0.44) | HSPA5HSPA2FDPSCYP3A4FFAR2 | |
| SCHEMBL17152395 | 0.80 | MMP9 (0.43) | HSPA5HSPA2AAK1CITFFAR2 | |
| SCHEMBL27228868 | 0.74 | FFAR2 (0.60) | HSPA5HSPA2AAK1CITFFAR2 | |
| SCHEMBL7873351 | 0.74 | FFAR2 (0.60) | HSPA5HSPA2AAK1CITFFAR2 | |
| SCHEMBL7279293 | 0.73 | ALOX12 (0.40) | HSPA5HSPA2AAK1CITSCN9A | |
| SCHEMBL7279299 | 0.73 | ALOX12 (0.40) | HSPA5HSPA2AAK1CITSCN9A | |
| SCHEMBL29637208 | 0.73 | CYP3A4 (0.56) | CYP3A4 | |
| SCHEMBL24387763 | 0.73 | FDPS (0.45) | HSPA5HSPA2FDPSCYP3A4AAK1 | |
| SCHEMBL27120255 | 0.73 | FDPS (0.45) | HSPA5HSPA2FDPSCYP3A4AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427939-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |