Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | FOLR1 | P15328 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SLC46A1 | Q96NT5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849931 | 0.98 | HPGD (0.43) | HPGDFOLR1MRGPRX4DHFRPARP1 | |
| SCHEMBL9849766 | 0.97 | HPGD (0.44) | HPGDFOLR1MRGPRX4DHFRPARP1 | |
| SCHEMBL9849692 | 0.93 | MRGPRX4 (0.38) | HPGDFOLR1MRGPRX4DHFRPARP1 | |
| SCHEMBL9849753 | 0.88 | FOLR1 (0.47) | FOLR1DHFRLMNAALDH1A1PRNP | |
| SCHEMBL9849759 | 0.85 | FOLR1 (0.44) | HPGDFOLR1DHFRLMNAATM | |
| SCHEMBL9850018 | 0.84 | FOLR1 (0.43) | HPGDFOLR1DHFRLMNAALDH1A1 | |
| SCHEMBL9849706 | 0.81 | DHFR (0.34) | HPGDDHFRNPSR1LMNAPPARG | |
| SCHEMBL9849782 | 0.80 | FOLR1 (0.41) | FOLR1MRGPRX4DHFRLMNAATM | |
| SCHEMBL9850059 | 0.78 | FOLR2 (0.39) | FOLR1DHFRSLC46A1 | |
| SCHEMBL9849619 | 0.77 | DHFR (0.33) | DHFRLMNAL3MBTL1ALDH1A1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415510-A2 | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4920125-A | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-04-24 | — | — | US | disclosed |