SCHEMBL9850139

SCHEMBL9850139

CCCC[Si](C)(C)OC(CCC)C(C(=O)O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.35
AKR1A1 P14550 1/20 0.35
CHRM3 P20309 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA2 P00918 1/20 0.35
MAPK1 P28482 1/20 0.35
GPR84 Q9NQS5 3/20 0.34
FFAR1 O14842 1/20 0.34
MAPT P10636 1/20 0.33
LCK P06239 1/20 0.33
PPARD Q03181 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8792932 0.75 CA2 (0.35) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5695216 0.74 CA2 (0.38) CA2MAPK1GPR84FFAR1MAPT
SCHEMBL2578866 0.73 GPR84 (0.46) CA2GPR84FFAR1MAPTLCK
SCHEMBL9323907 0.72 AKR1B1 (0.38) TDP1GPR84FFAR1PPARD
SCHEMBL8896852 0.71
SCHEMBL28176864 0.68 CA2 (0.43) TDP1CA2MAPK1SLC1A2SLC1A1
SCHEMBL14691652 0.67 TERT (0.44) CHRM1TDP1MAPTPPARD
SCHEMBL9850138 0.67 GPR84 (0.38) CA2MAPK1GPR84FFAR1MAPT
SCHEMBL28659058 0.66 AKR1B1 (0.36) TDP1GPR84FFAR1PPARD
SCHEMBL3042452 0.66 SPHK1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0409066-A2 Optically active compound for liquid crystal and its use MITSUBISHI RAYON COMPANY, LTD. (JP) 1991-01-23 EP disclosed