Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.45 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850128 | 0.89 | COXFA4 (0.47) | RXRACOXFA4DAGLAABHD6TDP1 | |
| SCHEMBL9850219 | 0.86 | RARA (0.52) | RXRACOXFA4DAGLAABHD6TDP1 | |
| SCHEMBL30195971 | 0.86 | RXRA (0.64) | RXRASSTR5COXFA4DAGLAABHD6 | |
| SCHEMBL3880185 | 0.86 | RXRA (0.64) | RXRASSTR5COXFA4DAGLAABHD6 | |
| SCHEMBL9850218 | 0.84 | MAPT (0.48) | RXRACOXFA4DAGLAABHD6TDP1 | |
| SCHEMBL9850284 | 0.84 | HIF1A (0.49) | RXRACOXFA4DAGLAABHD6TDP1 | |
| SCHEMBL16742142 | 0.82 | COXFA4 (0.53) | RXRASSTR5COXFA4DAGLAABHD6 | |
| SCHEMBL5712102 | 0.80 | RXRA (0.55) | RXRASSTR5COXFA4TDP1RXRB | |
| SCHEMBL6210404 | 0.79 | COXFA4 (0.50) | RXRASSTR5COXFA4TDP1MGAM | |
| SCHEMBL31026771 | 0.79 | COXFA4 (0.50) | RXRASSTR5COXFA4TDP1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5006550-A | Skin disorder, arthritis, wound healing agents, dry eye syndrome | ALLERGAN, INC. (US) | 1991-04-09 | — | — | US | disclosed |