Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 2/20 | 0.42 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16742142 | 0.91 | COXFA4 (0.53) | COXFA4RXRAMGAMGAASI | |
| SCHEMBL9850252 | 0.89 | RXRA (0.53) | COXFA4RXRAKMT2AMGAMGAA | |
| SCHEMBL9850219 | 0.87 | RARA (0.52) | COXFA4SRD5A1SRD5A2RXRAKMT2A | |
| SCHEMBL9850218 | 0.85 | MAPT (0.48) | COXFA4POLBRXRAKMT2ATDP1 | |
| SCHEMBL9850284 | 0.83 | HIF1A (0.49) | COXFA4SRD5A1SRD5A2RXRAKMT2A | |
| SCHEMBL9850207 | 0.79 | RARB (0.47) | POLBKMT2AACRHGFACHIF1A | |
| SCHEMBL15947259 | 0.78 | MAPT (0.47) | KMT2AGAATDP1MEN1MAPT | |
| SCHEMBL6210404 | 0.78 | COXFA4 (0.50) | COXFA4SRD5A1SRD5A2RXRAKMT2A | |
| SCHEMBL31026771 | 0.78 | COXFA4 (0.50) | COXFA4SRD5A1SRD5A2RXRAKMT2A | |
| SCHEMBL6210627 | 0.76 | RXRA (0.50) | COXFA4POLBRXRAKMT2AMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5006550-A | Skin disorder, arthritis, wound healing agents, dry eye syndrome | ALLERGAN, INC. (US) | 1991-04-09 | — | — | US | disclosed |