Sulfuric Acid

Sulfuric Acid

SCHEMBL9850303

CCNc1ccc(N)c(C)c1C(C)O.O=S(=O)(O)O

nearest known ligand 0.39

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
GFER P55789 1/20 0.39
PLEC Q15149 1/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
RECQL P46063 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL6550837 0.83 ALDH1A1 (0.35) MAPTKDM4EALDH1A1GAATHRB
SCHEMBL8359474 0.79 LMNA (0.38) MAPTKDM4EALDH1A1GAATHRB
Sulfuric Acid SCHEMBL6550045 0.74 KDM4E (0.39) MAPTKDM4EALDH1A1GAATHRB
Sulfuric Acid SCHEMBL10955650 0.73 KDM4E (0.38) MAPTKDM4EALDH1A1GAATHRB
Sulfuric Acid SCHEMBL6683793 0.73 MAPT (0.36) MAPTKDM4EALDH1A1GAATHRB
Sulfuric Acid SCHEMBL9614826 0.72 MAPT (0.35) MAPTKDM4EALDH1A1GAATHRB
SCHEMBL13560937 0.70 ALDH1A1 (0.49) MAPTKDM4EALDH1A1GAATHRB
SCHEMBL6708632 0.69 MAPT (0.32) MAPTKDM4EALDH1A1GAATHRB
Sulfuric Acid SCHEMBL7811899 0.69 LMNA (0.55) MAPTKDM4EALDH1A1GAATHRB
Hydrochloric Acid SCHEMBL27686457 0.69 ALDH1A1 (0.47) MAPTKDM4EALDH1A1GAATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449209-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-10-02 EP disclosed
US-4142897-A Gelatino silver halide photographic material hardened with a reaction product of a vinylsulfonyl compound and a water soluble compound KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-03-06 US disclosed