Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 5/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850630 | 0.92 | CYP19A1 (0.52) | CYP26A1CYP19A1 | |
| SCHEMBL11149385 | 0.86 | CYP19A1 (0.53) | CYP26A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9850618 | 0.85 | CHRM2 (0.52) | CYP26A1CYP19A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL9850632 | 0.84 | LMNA (0.51) | CYP26A1CYP19A1CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL9850662 | 0.83 | CHRM2 (0.54) | CYP19A1CYP2D6 | |
| SCHEMBL11154374 | 0.82 | CYP19A1 (0.67) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9850587 | 0.82 | POLB (0.52) | CYP26A1CYP19A1 | |
| SCHEMBL11144915 | 0.82 | CYP19A1 (0.60) | CYP19A1CYP3A4CYP1A2 | |
| SCHEMBL9850574 | 0.82 | SMN1; SMN2 (0.47) | CYP26A1CYP19A1CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL9850547 | 0.81 | TBXAS1 (0.49) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423524-A2 | Propiophenone derivatives and their preparation and pharmaceutical use | MARUHO Co., Ltd. (JP) | 1991-04-24 | — | — | EP | disclosed |