Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.45 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850630 | 0.84 | CYP19A1 (0.52) | POLBTBXAS1CYP19A1ALDH1A1CYP26A1 | |
| SCHEMBL9850426 | 0.82 | CYP26A1 (0.61) | CYP19A1CYP26A1 | |
| SCHEMBL9850634 | 0.82 | L3MBTL1 (0.44) | TBXAS1CYP19A1ALDH1A1CYP26A1L3MBTL1 | |
| SCHEMBL9850632 | 0.82 | LMNA (0.51) | CYP19A1CYP26A1 | |
| SCHEMBL11149385 | 0.81 | CYP19A1 (0.53) | TBXAS1CYP19A1ALDH1A1GAACYP26A1 | |
| SCHEMBL9850618 | 0.80 | CHRM2 (0.52) | TBXAS1CYP19A1ALDH1A1CYP26A1 | |
| SCHEMBL11144915 | 0.80 | CYP19A1 (0.60) | TBXAS1CYP19A1ALDH1A1GAAMAPK1 | |
| SCHEMBL9850420 | 0.79 | CYP17A1 (0.55) | TBXAS1KDM4ECYP26A1L3MBTL1 | |
| SCHEMBL9850662 | 0.78 | CHRM2 (0.54) | TBXAS1CYP19A1 | |
| SCHEMBL11154374 | 0.78 | CYP19A1 (0.67) | TBXAS1CYP19A1ALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423524-A2 | Propiophenone derivatives and their preparation and pharmaceutical use | MARUHO Co., Ltd. (JP) | 1991-04-24 | — | — | EP | disclosed |