Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850547 | 0.90 | TBXAS1 (0.49) | TBXAS1CYP19A1 | |
| SCHEMBL9850618 | 0.86 | CHRM2 (0.52) | CHRM2CYP2D6ADRA2BDRD3SIGMAR1 | |
| SCHEMBL9850632 | 0.85 | LMNA (0.51) | CYP2D6CYP19A1 | |
| SCHEMBL9850630 | 0.85 | CYP19A1 (0.52) | TBXAS1CYP19A1 | |
| Hydrochloric Acid SCHEMBL9850390 | 0.84 | TBXAS1 (0.47) | TBXAS1CYP19A1PDE4APDE4BPDE4C | |
| SCHEMBL9850440 | 0.84 | CYP19A1 (0.50) | TBXAS1CYP19A1 | |
| SCHEMBL11144915 | 0.83 | CYP19A1 (0.60) | TBXAS1CYP19A1 | |
| SCHEMBL9850574 | 0.83 | SMN1; SMN2 (0.47) | CYP2D6CYP19A1 | |
| SCHEMBL9850426 | 0.83 | CYP26A1 (0.61) | CYP2D6CYP19A1 | |
| SCHEMBL9850634 | 0.80 | L3MBTL1 (0.44) | TBXAS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423524-A2 | Propiophenone derivatives and their preparation and pharmaceutical use | MARUHO Co., Ltd. (JP) | 1991-04-24 | — | — | EP | disclosed |