Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850424 | 0.84 | HTR1A (0.54) | MAPTKDM4EINSRIGF1RRAB9A | |
| SCHEMBL9850444 | 0.83 | INSR (0.41) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9850498 | 0.82 | BCHE (0.49) | MAPTKDM4EALDH1A1SMN1; SMN2BCHE | |
| SCHEMBL9850544 | 0.81 | CA12 (0.53) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9850536 | 0.74 | ALDH1A1 (0.70) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9850546 | 0.73 | ALDH1A1 (0.60) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7572085 | 0.72 | RECQL (0.58) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10936657 | 0.72 | INSR (0.55) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7571372 | 0.72 | INSR (0.58) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9850339 | 0.72 | FADS1 (0.60) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |