Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3777821 | 0.82 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13952491 | 0.78 | POLB (0.44) | KDM4EALDH1A1HPGDPOLBL3MBTL1 | |
| SCHEMBL9850735 | 0.78 | CNR2 (0.50) | FABP4FABP5KDM4EPOLBHTT | |
| SCHEMBL11296052 | 0.77 | FABP4 (0.59) | FABP4FABP5KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL18727718 | 0.75 | KDM4E (0.49) | KDM4EALDH1A1HPGDHTTKMT2A | |
| SCHEMBL11985534 | 0.75 | KDM4E (0.49) | KDM4EALDH1A1HPGDHTTKMT2A | |
| SCHEMBL13767381 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDPOLBL3MBTL1 | |
| SCHEMBL22965217 | 0.73 | KMO (0.51) | FABP4FABP5KDM4EPOLBL3MBTL1 | |
| SCHEMBL17580969 | 0.72 | KDM4E (0.73) | FABP4FABP5KDM4EALDH1A1HPGD | |
| SCHEMBL3778294 | 0.72 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416740-A2 | Novel compounds with renin-inhibiting activity | Beecham Group p.l.c. (GB) | 1991-03-13 | — | — | EP | disclosed |