Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPM1D | O15297 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851003 | 0.90 | ALDH1A1 (0.46) | KMT2AMEN1KDM4ESOAT2SOAT1 | |
| SCHEMBL9851046 | 0.89 | KMT2A (0.49) | KMT2AMEN1KDM4ESOAT2SOAT1 | |
| SCHEMBL9850979 | 0.79 | NLRP3 (0.43) | KMT2AMEN1KDM4ESOAT2SOAT1 | |
| SCHEMBL9680212 | 0.73 | KMT2A (0.54) | KMT2AMEN1KDM4ESOAT2SOAT1 | |
| SCHEMBL9680238 | 0.73 | SOAT2 (0.52) | KMT2AMEN1KDM4ESOAT2SOAT1 | |
| SCHEMBL9463084 | 0.71 | KMT2A (0.67) | KMT2AMEN1KDM4ESOAT2SOAT1 | |
| SCHEMBL9316324 | 0.70 | KMT2A (0.69) | KMT2AMEN1KDM4ESOAT2SOAT1 | |
| SCHEMBL9679236 | 0.69 | KMT2A (0.52) | KMT2AMEN1KDM4ESOAT2SOAT1 | |
| SCHEMBL9680654 | 0.68 | KMT2A (0.56) | KMT2AMEN1KDM4ESOAT2SOAT1 | |
| SCHEMBL9679838 | 0.67 | SOAT1 (0.56) | KMT2AMEN1KDM4ESOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |