Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850989 | 0.90 | KMT2A (0.47) | KMT2AMEN1KDM4ESOAT2SOAT1 | |
| SCHEMBL9851046 | 0.81 | KMT2A (0.49) | ALDH1A1HTTKMT2AMEN1KDM4E | |
| SCHEMBL9850979 | 0.81 | NLRP3 (0.43) | ALDH1A1HTTKMT2AMEN1KDM4E | |
| SCHEMBL9679584 | 0.73 | KMT2A (0.51) | KMT2AMEN1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9851069 | 0.69 | LOXL2 (0.61) | ALDH1A1KDM4ELOXL2SMN1; SMN2HIF1A | |
| SCHEMBL307687 | 0.69 | LOXL2 (0.61) | ALDH1A1KMT2AMEN1KDM4ELOXL2 | |
| SCHEMBL1458108 | 0.69 | LOXL2 (0.57) | ALDH1A1KMT2AMEN1KDM4ELOXL2 | |
| SCHEMBL9680238 | 0.69 | SOAT2 (0.52) | KMT2AMEN1KDM4ESOAT2SOAT1 | |
| SCHEMBL2069334 | 0.68 | LOXL2 (0.68) | ALDH1A1KDM4ELOXL2LMNASMN1; SMN2 | |
| SCHEMBL13822327 | 0.68 | MRGPRX4 (0.55) | ALDH1A1KMT2AMEN1KDM4ELOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |