Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851046 | 0.87 | KMT2A (0.49) | KMT2AMEN1KDM4EALDH1A1HTT | |
| SCHEMBL9851003 | 0.81 | ALDH1A1 (0.46) | KMT2AMEN1KDM4EALDH1A1HTT | |
| SCHEMBL9850989 | 0.79 | KMT2A (0.47) | KMT2AMEN1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9681138 | 0.76 | MEN1 (0.53) | NLRP3KMT2AMEN1 | |
| SCHEMBL2147884 | 0.68 | NLRP3 (0.70) | NLRP3KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8689258 | 0.68 | MEN1 (0.61) | KMT2AMEN1KDM4EALDH1A1HTT | |
| SCHEMBL9678682 | 0.67 | LMNA (0.57) | KMT2AMEN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9679236 | 0.67 | KMT2A (0.52) | KMT2AMEN1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL28188485 | 0.67 | NLRP3 (0.81) | NLRP3KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9680238 | 0.66 | SOAT2 (0.52) | KMT2AMEN1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |