SCHEMBL166835

SCHEMBL166835

CCCCCCCCCCN(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.53
JAK2 O60674 1/20 0.53
RAB9A P51151 1/20 0.53
PAX8 Q06710 1/20 0.53
KCNH2 Q12809 5/20 0.50
MEN1 O00255 1/20 0.45
CASP1 P29466 1/20 0.45
BRCA1 P38398 1/20 0.45
CASP7 P55210 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HSD17B10 Q99714 1/20 0.45
ALDH1A1 P00352 1/20 0.44
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TACR1 P25103 1/20 0.44
SIGMAR1 Q99720 3/20 0.44
DHFR P00374 2/20 0.43
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44732 1.00 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL28622552 1.00 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL1204768 1.00 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL7924615 1.00 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL2849795 1.00 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL985190 1.00 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL60682 1.00 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL619876 1.00 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL45379 1.00 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL983245 1.00 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 827 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190277339-A1 COMPOSITION OF HIGH PERFORMANCE BEARING OIL FOR STEEL PLANTS INDIAN OIL CORPORATION LIMITED (IN) 2019-09-12 US claimed
EP-3536768-A1 NOVEL COMPOSITION OF HIGH PERFORMANCE BEARING OIL FOR STEEL PLANTS Indian Oil Corporation Limited (IN) 2019-09-11 EP claimed
US-7534747-B2 Gels that reduce soot and/or emissions from engines THE LUBRIZOL CORPORATION (US) 2009-05-19 US claimed
WO-2006022724-A1 GELS THAT REDUCE SOOT AND/OR EMISSIONS FROM ENGINES THE LUBRIZOL CORPORATION (US) 2006-03-02 WO claimed
US-20040266631-A1 Gels that reduce soot and/or emissions from engines THE LUBRIZOL CORPORATION 2004-12-30 US claimed
US-20260139197-A1 HYDRAULIC FLUID COMPOSITION THE LUBRIZOL CORPORATION (US) 2026-05-21 US disclosed
EP-4488349-B1 AZOLE DERIVATIVES AS LUBRICATING ADDITIVES LUBRIZOL CORP (US) 2026-05-20 EP disclosed
US-12606767-B2 1,4-benzoxazine compounds and lubricant compositions containing the same THE LUBRIZOL CORPORATION (US) 2026-04-21 US disclosed
EP-4377426-B1 1,4-BENZOXAZINE COMPOUNDS AND LUBRICANT COMPOSITIONS CONTAINING THE SAME LUBRIZOL CORP (US) 2026-04-15 EP disclosed
EP-4717753-A2 LUBRICANT COMPOSITIONS FOR DIRECT INJECTION ENGINES The Lubrizol Corporation (US) 2026-04-01 EP disclosed
EP-4713506-A1 ADDITIVES FOR IMPROVED ELECTROLYZER DURABILITY The Lubrizol Corporation (US) 2026-03-25 EP disclosed
EP-4713505-A1 ADDITIVES FOR IMPROVED ELECTROLYZER DURABILITY The Lubrizol Corporation (US) 2026-03-25 EP disclosed
US-20040266630-A1 Novel additive composition that reduces soot and/or emissions from engines THE LUBRIZOL CORPORATION, A CORPORATION OF THE STATE OF OHIO 2004-12-30 US disclosed
WO-2004113479-A1 LUBRICATING OIL COMPOSITION WITH ANTIWEAR PERFORMANCE THE LUBRIZOL CORPORATION (US) 2004-12-29 WO disclosed
US-20040259743-A1 Lubricating oil composition with antiwear performance THE LUBRIZOL CORPORATION, A CORPORATION OF THE STATE OF OHIO 2004-12-23 US disclosed
US-6797677-B2 PARTICULARLY SUITED FOR USE AS A CRANKCASE LUBRICANT, OR A TRANSMISSION LUBRICANT, INCLUDING LOW LEVELS AND ZERO LEVELS OF PHOSPHORUS. AFTON CHEMICAL CORPORATION 2004-09-28 US disclosed
CN-1461800-A Antioxygen composition for oxydization and diposite controll in lubricant containing molybdenum and alky phenol thiazine ETHYL CORP (US) 2003-12-17 CN disclosed
EP-1369469-A1 An antioxidant additives combination for lubricants containing a molybdenum complex and an alkylated phenothiazine ETHYL CORPORATION (US) 2003-12-10 EP disclosed
US-20030224950-A1 Antioxidant combination for oxidation and deposit control in lubricants containing molybdenum and alkylated phenothiazine AFTON CHEMICAL CORPORATION 2003-12-04 US disclosed
US-5614124-A OILS WITH ANTIOXIDANT-DISPERSANTS OF POLYOLEFIN SUCCINIMIDE AND PHENOTHIAZINE ETHYL ADDITIVES CORPORATION (US) 1997-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606767-B2 1,4-benzoxazine compounds and lubricant compositions containing the same PRDX4, PRDX1, GPX4 NPC1 4047/4885JAK2 2533/4885RAB9A 4610/4885
US-20260139197-A1 HYDRAULIC FLUID COMPOSITION SRM, SUGT1, SMS NPC1 1734/4885JAK2 1270/4885RAB9A 3571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.