Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.55 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727095 | 0.87 | DRD4 (0.72) | DRD4MAOBSIGMAR1MCHR1ALDH1A1 | |
| SCHEMBL9852082 | 0.85 | DRD4 (0.73) | DRD4MAOBSIGMAR1MCHR1ACHE | |
| SCHEMBL9852060 | 0.81 | ACHE (0.60) | DRD4SIGMAR1MCHR1POLBALDH1A1 | |
| Iodide SCHEMBL9852255 | 0.79 | DRD4 (0.60) | DRD4MAOBSIGMAR1MCHR1ACHE | |
| SCHEMBL9727135 | 0.79 | DRD4 (0.67) | DRD4MAOBSIGMAR1MCHR1 | |
| SCHEMBL9727235 | 0.78 | DRD4 (0.58) | DRD4MAOBSIGMAR1MCHR1ACHE | |
| SCHEMBL9727088 | 0.78 | DRD4 (0.62) | DRD4MAOBSIGMAR1MCHR1 | |
| Dimethylamine SCHEMBL9852061 | 0.78 | DRD4 (0.63) | DRD4MAOBSIGMAR1MCHR1POLB | |
| SCHEMBL9727149 | 0.78 | DRD4 (0.58) | DRD4MAOBSIGMAR1MCHR1ALDH1A1 | |
| SCHEMBL9852087 | 0.77 | DRD4 (0.61) | DRD4MAOBSIGMAR1MCHR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |