Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.55 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.55 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852220 | 0.93 | DRD4 (0.64) | CHRNA7SIGMAR1MAOBDRD4TMEM97 | |
| SCHEMBL9727131 | 0.80 | MAOB (0.74) | MAOBDRD4SLC6A12SLC6A13ACHE | |
| SCHEMBL9482226 | 0.80 | SIGMAR1 (0.55) | SIGMAR1MAOBDRD4SLC6A12SLC6A13 | |
| SCHEMBL9852247 | 0.80 | SIGMAR1 (0.59) | SIGMAR1MAOBDRD4TMEM97SLC6A12 | |
| SCHEMBL9727243 | 0.80 | DRD4 (0.69) | SIGMAR1MAOBDRD4MAPK1ACHE | |
| SCHEMBL3598699 | 0.79 | SIGMAR1 (0.66) | SIGMAR1TMEM97SLC6A12MAPK1L3MBTL1 | |
| SCHEMBL4894227 | 0.76 | MCHR1 (0.79) | SIGMAR1DRD4TMEM97SLC6A12SLC6A13 | |
| SCHEMBL3604610 | 0.76 | SLC6A12 (0.64) | SIGMAR1DRD4TMEM97SLC6A12MAPK1 | |
| SCHEMBL9868364 | 0.76 | SIGMAR1 (0.61) | SIGMAR1DRD4TMEM97SLC6A12MAPK1 | |
| SCHEMBL2978252 | 0.75 | SIGMAR1 (0.63) | SIGMAR1TMEM97SLC6A12L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |