Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.59 |
| ▸ | DRD4 | P21917 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.52 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.52 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852241 | 0.93 | DRD4 (0.60) | SIGMAR1DRD4MAPK1TMEM97 | |
| SCHEMBL9727135 | 0.81 | DRD4 (0.67) | SIGMAR1DRD4MAPK1TMEM97SLC6A12 | |
| SCHEMBL9482240 | 0.80 | DRD4 (0.53) | SIGMAR1DRD4MAPK1TMEM97SLC6A12 | |
| SCHEMBL9727255 | 0.80 | DRD4 (0.66) | SIGMAR1DRD4TMEM97MAOB | |
| SCHEMBL9852232 | 0.80 | CHRNA7 (0.60) | SIGMAR1DRD4MAPK1TMEM97SLC6A12 | |
| Dimethylamine SCHEMBL9852061 | 0.78 | DRD4 (0.63) | SIGMAR1DRD4SLC6A12SLC6A13MAOB | |
| SCHEMBL3598699 | 0.78 | SIGMAR1 (0.66) | SIGMAR1MAPK1TMEM97SLC6A12L3MBTL1 | |
| SCHEMBL3604610 | 0.75 | SLC6A12 (0.64) | SIGMAR1DRD4MAPK1TMEM97SLC6A12 | |
| SCHEMBL9727088 | 0.75 | DRD4 (0.62) | SIGMAR1DRD4SLC6A12MAOB | |
| SCHEMBL9727190 | 0.75 | DRD4 (0.62) | SIGMAR1DRD4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |