Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727091 | 0.88 | DRD4 (0.70) | ACHEKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9852062 | 0.86 | DRD4 (0.71) | ACHEKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9852245 | 0.81 | DRD4 (0.55) | ACHEALDH1A1MCHR1DRD4SIGMAR1 | |
| SCHEMBL9727131 | 0.80 | MAOB (0.74) | ACHEMCHR1KCNH2UTS2RDRD4 | |
| Iodide SCHEMBL9852252 | 0.79 | DRD4 (0.59) | ACHEKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4917286 | 0.79 | TP53 (0.67) | KDM4EALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL9727140 | 0.79 | UTS2R (0.73) | ACHEKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6333472 | 0.78 | MCHR1 (0.69) | ACHEMCHR1KCNH2DRD4BCHE | |
| SCHEMBL9852064 | 0.78 | MCHR1 (0.66) | ACHEKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9727082 | 0.78 | DRD4 (0.64) | ACHEKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |