Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 7/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852809 | 0.89 | ALPL (0.47) | ALPLFBP1SLC40A1AXLSLC22A12 | |
| SCHEMBL9618654 | 0.84 | FBP1 (0.48) | ALPLFBP1SLC40A1AXLSLC22A12 | |
| SCHEMBL30549039 | 0.81 | ALPL (0.47) | ALPLFBP1SLC40A1AXLSLC22A12 | |
| SCHEMBL7227108 | 0.80 | FBP1 (0.49) | ALPLFBP1SLC40A1AXLSLC22A12 | |
| SCHEMBL10686865 | 0.74 | NR1H4 (0.44) | ALPLFBP1SLC40A1SLC22A12MRGPRX1 | |
| SCHEMBL8438519 | 0.74 | ALPL (0.43) | ALPLFBP1SLC40A1AXLSLC22A12 | |
| SCHEMBL7227192 | 0.74 | FBP1 (0.51) | ALPLFBP1SLC40A1AXLSLC22A12 | |
| Benzene SCHEMBL10690567 | 0.73 | KMT2A (0.46) | ALPLSLC40A1SLC22A12MRGPRX1PTGER4 | |
| SCHEMBL25248899 | 0.73 | ALPL (0.49) | ALPLFBP1SLC40A1SLC22A12MRGPRX1 | |
| SCHEMBL10695682 | 0.72 | MAPT (0.46) | ALPLFBP1SLC40A1SLC22A12PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444286-A1 | Sulphonylated pyrimidine carboxylic acid amides | BAYER AG (DE) | 1991-09-04 | — | — | EP | disclosed |