Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BRD1 | O95696 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388680 | 0.80 | THRB (0.52) | THRBHPGDTSHRL3MBTL1GAA | |
| SCHEMBL7552123 | 0.79 | KAT6A (0.52) | TSHRKAT6APKMSLC40A1RAD52 | |
| SCHEMBL9852812 | 0.74 | NPSR1 (0.47) | THRBTSHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9357229 | 0.74 | HSD17B10 (0.42) | THRBHPGDTSHRRAPGEF3ALDH1A1 | |
| SCHEMBL10761883 | 0.71 | HPGD (0.45) | HCRTR1HCRTR2THRBHPGDTSHR | |
| SCHEMBL9852795 | 0.70 | ALPL (0.45) | SLC40A1RAPGEF3 | |
| SCHEMBL2994281 | 0.70 | KDM4E (0.47) | KAT6ASLC40A1ALDH1A1KDM4EGAA | |
| SCHEMBL6620390 | 0.69 | HTR6 (0.49) | HPGDTSHRKAT6APKMSLC40A1 | |
| SCHEMBL9852809 | 0.69 | ALPL (0.47) | SLC40A1BRD4 | |
| SCHEMBL8224006 | 0.68 | HTR6 (0.55) | TSHRKAT6APKMSLC40A1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444286-A1 | Sulphonylated pyrimidine carboxylic acid amides | BAYER AG (DE) | 1991-09-04 | — | — | EP | disclosed |