Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6104432 | 0.77 | GRIN1 (0.45) | MTNR1AMTNR1BCYP3A4 | |
| SCHEMBL5252222 | 0.76 | SIGMAR1 (0.46) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL146771 | 0.76 | MTNR1A (0.55) | MTNR1AMTNR1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9852967 | 0.75 | MTNR1A (0.57) | MTNR1AMTNR1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28703461 | 0.74 | MTNR1A (0.56) | MTNR1AMTNR1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28696042 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1BSLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL30185866 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9852986 | 0.72 | MTNR1A (0.53) | MTNR1AMTNR1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2073609 | 0.72 | TAAR1 (0.57) | ALDH1A1 | |
| SCHEMBL7661102 | 0.71 | MTNR1A (0.45) | MTNR1AMTNR1BSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |