Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.39 |
| ▸ | DHPS | P49366 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985699 | 0.83 | MTOR (0.37) | EGFRMTOR | |
| SCHEMBL985268 | 0.72 | DHPS (0.36) | DHPS | |
| SCHEMBL15921329 | 0.66 | ACHE (0.43) | DHPS | |
| SCHEMBL2801074 | 0.62 | NR1H4 (0.50) | — | |
| SCHEMBL1353468 | 0.62 | AHR (0.44) | DHPS | |
| SCHEMBL28368568 | 0.62 | NPC1 (0.58) | — | |
| SCHEMBL10111230 | 0.62 | AHR (0.44) | DHPS | |
| SCHEMBL986284 | 0.61 | RAB9A (0.35) | — | |
| SCHEMBL7849702 | 0.61 | MEN1 (0.53) | DHPS | |
| SCHEMBL11290759 | 0.60 | LMNA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012099581-A1 | DIHYDROFUROPYRIMIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-07-26 | — | — | WO | disclosed |
| US-20110021515-A1 | DIHYROFUROPYRMINDINE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021515-A1 | DIHYROFUROPYRMINDINE COMPOUNDS | MTOR, RICTOR, DEPTOR | EGFR 2918/4885DHPS 20/4885MTOR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.