Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888927 | 0.75 | ALDH1A1 (0.50) | ALDH1A1ALOX15HPGDHSD17B10CA2 | |
| SCHEMBL9853388 | 0.71 | ALDH1A1 (0.45) | ALDH1A1ALOX15HPGDHSD17B10CA2 | |
| SCHEMBL3917019 | 0.71 | ALOX15 (0.45) | ALDH1A1ALOX15HPGDHSD17B10CA2 | |
| SCHEMBL7513765 | 0.70 | ALOX15 (0.52) | ALDH1A1ALOX15HPGDHSD17B10CA2 | |
| SCHEMBL6274433 | 0.69 | USP2 (0.70) | ALDH1A1HPGDHSD17B10RECQLTDP1 | |
| SCHEMBL5179392 | 0.69 | — | — | |
| SCHEMBL24718435 | 0.65 | ALDH1A1 (0.39) | ALDH1A1ALOX15HPGDHSD17B10CA2 | |
| SCHEMBL10887948 | 0.65 | TSHR (0.54) | ALDH1A1ALOX15HPGDHSD17B10CA2 | |
| SCHEMBL2865709 | 0.65 | ALDH1A1 (0.43) | ALDH1A1ALOX15HPGDHSD17B10CA2 | |
| SCHEMBL1358980 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119103-B2 | Bifunctional resorcinol, thioresorcinol, and dithioresorcinol derivative metal chelating conjugates | MALLINCKRODT LLC (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100055043-A1 | Poly-Halo Metal X-ray Contrast Agents | MALLINCKRODT INC. | 2010-03-04 | — | — | US | disclosed |
| EP-2089063-A2 | X-RAY CONTRAST AGENTS COMPRISING A METAL CHELATE AND A POLYHALOGENATED PHENOL, THIOPHENOL, RESORCINOL, THIORESORCINOL OR DITHIORESORCINOL | Mallinckrodt Inc. (US) | 2009-08-19 | — | — | EP | disclosed |
| US-20090082324-A1 | Bifunctional Resorcinol, Thioresorcinol, and Dithioresorcinol Derivative Metal Chelating Conjugates | INFACARE PHARMACEUTICAL CORPORATION | 2009-03-26 | — | — | US | disclosed |
| EP-1988925-A2 | BIFUNCTIONAL RESORCINOL, THIORESORCINOL, AND DITHIORESORCINOL DERIVATIVE METAL CHELATING CONJUGATES | MALLINCKRODT, INC. (US) | 2008-11-12 | — | — | EP | disclosed |
| WO-2008060399-A2 | X-RAY CONTRAST AGENTS COMPRISING A METAL CHELATE AND A POLYHALOGENATED PHENOL, THIOPHENOL, RESORCINOL, THIORESORCINOL OR DITHIORESORCINOL | MALLINCKRODT INC. (US) | 2008-05-22 | — | — | WO | disclosed |
| WO-2007100563-A2 | BIFUNCTIONAL RESORCINOL, THIORESORCINOL, AND DITHIORESORCINOL DERIVATIVE METAL CHELATING CONJUGATES | MALLINCKRODT INC. (US) | 2007-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082324-A1 | Bifunctional Resorcinol, Thioresorcinol, and Dithioresorcinol Derivative Metal Chelating Conjugates | SPR, QDPR, SLC40A1 | ALDH1A1 716/4885ALOX15 4499/4885HPGD 2378/4885 |
| US-20100055043-A1 | Poly-Halo Metal X-ray Contrast Agents | SLC39A3, ZNF277, TPR | ALDH1A1 3268/4885ALOX15 4178/4885HPGD 2704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.