Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CBX7 | O95931 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853446 | 0.79 | MCHR1 (0.34) | MAPTL3MBTL1HTTSMN1; SMN2TDP1 | |
| SCHEMBL9853449 | 0.73 | SRD5A2 (0.40) | MAPTL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL8180147 | 0.71 | NPC1 (0.47) | MAPTL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL9654477 | 0.70 | MAOB (0.50) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9853510 | 0.70 | PDE4A (0.34) | MAPTL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL8566318 | 0.68 | AR (0.37) | RAB9ASMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL10702555 | 0.68 | ALDH1A1 (0.50) | MAPTL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL9853445 | 0.67 | MAPT (0.41) | MAPTHTTPOLB | |
| SCHEMBL10995463 | 0.67 | MAPK1 (0.65) | MAPTSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL10983597 | 0.67 | MAPK1 (0.65) | MAPTSMN1; SMN2TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446718-A2 | Phenoxy bis-maleimides and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |