Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853454 | 0.78 | MAPT (0.39) | MAPTNPC1POLBBRAFHPGD | |
| SCHEMBL9853445 | 0.74 | MAPT (0.41) | PDE4APDE4DMAPTHTTHDAC2 | |
| SCHEMBL9853449 | 0.73 | SRD5A2 (0.40) | MAPTL3MBTL1NPC1HTTRAB9A | |
| SCHEMBL9853442 | 0.70 | MAPT (0.37) | MAPTL3MBTL1NPC1HTTRAB9A | |
| SCHEMBL8566318 | 0.69 | AR (0.37) | RAB9ATDP1 | |
| SCHEMBL28337654 | 0.67 | MAOA (0.47) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL27780001 | 0.67 | GSK3A (0.42) | MAPTL3MBTL1TDP1POLBHPGD | |
| SCHEMBL28940515 | 0.67 | KMT2A (0.58) | MAPTL3MBTL1RAB9ATDP1POLB | |
| SCHEMBL28880029 | 0.67 | MAOB (0.52) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL16980249 | 0.66 | CYP3A4 (0.45) | MAPTL3MBTL1NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446718-A2 | Phenoxy bis-maleimides and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |