Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853450 | 0.89 | KDM4E (0.37) | MCHR1KDM4ETSHRMRGPRX4PTGDR2 | |
| SCHEMBL9853442 | 0.79 | MAPT (0.37) | KDM4EL3MBTL1TDP1PPARGPPARD | |
| SCHEMBL9853447 | 0.73 | BACE1 (0.35) | KDM4ETSHRMAPK1L3MBTL1LMNA | |
| SCHEMBL8175332 | 0.71 | ALDH1A1 (0.43) | KDM4ETSHRMAPK1L3MBTL1HDAC3 | |
| SCHEMBL9853454 | 0.70 | MAPT (0.39) | KDM4EHPGDPTGDR2LMNACYP1A2 | |
| SCHEMBL942491 | 0.69 | VDR (0.51) | MCHR1HDAC3HDAC6VDRALDH1A1 | |
| SCHEMBL20496732 | 0.68 | ALDH1A1 (0.53) | KDM4ETSHRMAPK1L3MBTL1LMNA | |
| SCHEMBL9853451 | 0.68 | SRC (0.41) | MAPK1CYP1A2BRD4MEN1TP53 | |
| SCHEMBL9654477 | 0.67 | MAOB (0.50) | TSHRHPGDMAPK1L3MBTL1TDP1 | |
| SCHEMBL2565945 | 0.67 | ALDH1A1 (0.52) | MCHR1KDM4ETSHRL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446718-A2 | Phenoxy bis-maleimides and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | claimed |
| EP-0446718-A2 | Phenoxy bis-maleimides and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |