Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | IGLV6-57 | P01721 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298221 | 0.87 | SRD5A2 (0.45) | SRD5A2F2IGLV6-57TDP1MEN1 | |
| SCHEMBL9853447 | 0.76 | BACE1 (0.35) | BRD4TDP1MEN1KMT2ANPC1 | |
| SCHEMBL9853510 | 0.73 | PDE4A (0.34) | TDP1NPC1MAPTHTTRAB9A | |
| SCHEMBL9853442 | 0.73 | MAPT (0.37) | TDP1MEN1KMT2ANPC1MAPT | |
| SCHEMBL9853445 | 0.72 | MAPT (0.41) | SRD5A2MAPTHTTALDH1A1 | |
| SCHEMBL9860015 | 0.72 | SRD5A2 (0.45) | SRD5A2F2IGLV6-57TDP1MEN1 | |
| SCHEMBL8566318 | 0.71 | AR (0.37) | TDP1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9853722 | 0.69 | SRD5A2 (0.49) | SRD5A2F2IGLV6-57TDP1MEN1 | |
| SCHEMBL11095278 | 0.67 | IDO1 (0.41) | TDP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16756041 | 0.66 | ALDH1A1 (0.46) | BRD4TDP1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446718-A2 | Phenoxy bis-maleimides and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |