Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853446 | 0.89 | MCHR1 (0.34) | KDM4ESCN4AVDRALDH1A1MRGPRX4 | |
| SCHEMBL8175332 | 0.80 | ALDH1A1 (0.43) | KDM4EVDRALDH1A1AAK1HDAC3 | |
| SCHEMBL942491 | 0.78 | VDR (0.51) | VDRALDH1A1MCHR1HDAC3HDAC6 | |
| SCHEMBL2565945 | 0.76 | ALDH1A1 (0.52) | KDM4EALDH1A1MCHR1AAK1GAA | |
| SCHEMBL9654477 | 0.76 | MAOB (0.50) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL508229 | 0.75 | NUDT1 (0.47) | KDM4EVDRALDH1A1AAK1HDAC3 | |
| SCHEMBL1407008 | 0.74 | FFAR4 (0.56) | MRGPRX4GAAMAPTHTTTDP1 | |
| SCHEMBL20496732 | 0.73 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL20496733 | 0.73 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL8542281 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446718-A2 | Phenoxy bis-maleimides and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |