Biotin

Biotin

SCHEMBL985362

N=C=S.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.85

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.85
▸ MEN1 O00255 1/20 0.85
▸ ABL1 P00519 1/20 0.85
▸ LMNA P02545 1/20 0.85
▸ PKM P14618 1/20 0.85
▸ IDE P14735 1/20 0.85
▸ MAPK1 P28482 1/20 0.85
▸ KMT2A Q03164 1/20 0.85
▸ RIN1 Q13671 1/20 0.85
▸ L3MBTL1 Q9Y468 1/20 0.85
▸ HLCS P50747 6/20 0.60
▸ CA12 O43570 7/20 0.50
▸ CA1 P00915 7/20 0.50
▸ CA2 P00918 7/20 0.50
▸ CA9 Q16790 7/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL3827271 0.94 TDP1 (0.87) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL19988310 0.92 TDP1 (0.94) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL38817 0.92 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL8763 0.92 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL10047687 0.92 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL23055065 0.92 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL20547409 0.92 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL21981206 0.92 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL22943835 0.92 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL14489489 0.92 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260086095-A1 METHODS FOR DETECTION OF PROSTATE CANCER, RELATED BIOMARKERS AND KITS FOR DETERMINING THE BIOMARKERS OY ARCTIC PARTNERS AB (FI) 2026-03-26 — — US disclosed
EP-4581365-A1 METHODS FOR DETECTION OF PROSTATE CANCER, RELATED BIOMARKERS AND KITS FOR DETERMINING THE BIOMARKERS OY Arctic Partners AB (FI) 2025-07-09 — — EP disclosed
US-20250208144-A1 ASSAY FOR LONG FORMS OF CARDIAC TROPONIN T TURUN YLIOPISTO (FI) 2025-06-26 — — US disclosed
US-20250102510-A1 LECTIN-BASED DIAGNOSTICS OF CANCERS UNIOGEN OY (FI) 2025-03-27 — — US disclosed
EP-4500188-A1 ASSAY FOR LONG FORMS OF CARDIAC TROPONIN T Turun yliopisto (FI) 2025-02-05 — — EP disclosed
US-12196756-B2 Lectin-based diagnostics of cancers UNIOGEN OY (FI) 2025-01-14 — — US disclosed
CN-119137480-A Assay for long form cardiac troponin T 图尔库大学 2024-12-13 — — CN disclosed
WO-2024047283-A1 METHODS FOR DETECTION OF PROSTATE CANCER, RELATED BIOMARKERS AND KITS FOR DETERMINING THE BIOMARKERS OY ARCTIC PARTNERS AB (FI) 2024-03-07 — — WO disclosed
US-20230393137-A1 COMPOSITIONS AND METHODS RELATED TO DIAGNOSIS OF PROSTATE CANCER OPKO DIAGNOSTICS, LLC (US) 2023-12-07 — — US disclosed
EP-3123381-B1 COMPOSITIONS AND METHODS RELATED TO DIAGNOSIS OF PROSTATE CANCER OPKO DIAGNOSTICS LLC (US) 2023-10-11 — — EP disclosed
US-6967081-B1 Method for prediction of bone fractures by osteocalcin measurements KAEKOENEN SANNA-MARIA 2005-11-22 — — US disclosed
WO-2005073727-A1 IMPROVED METHOD FOR DIAGNOSING ACUTE CORONARY SYNDROME TURUN YLIOPISTO (FI) 2005-08-11 — — WO disclosed
US-20040259167-A1 gamma-carboxylated osteocalcin of given sequence, where a specified glutamic acid is gamma-carboxylated; derived from human urine; use to measure rate of bone turnover in metabolic bone disorders HELLMAN JUKKA (FI) 2004-12-23 — — US disclosed
EP-1166122-A1 METHOD FOR PREDICTION OF BONE FRACTURES BY OSTEOCALCIN MEASUREMENTS Käkonen, Sanna-Maria (FI) 2002-01-02 — — EP disclosed
WO-2000058732-A1 METHOD FOR PREDICTION OF BONE FRACTURES BY OSTEOCALCIN MEASUREMENTS KAEKOENEN SANNA MARIA (FI) 2000-10-05 — — WO disclosed
EP-1003778-A1 ISOLATED OSTEOCALCIN FRAGMENTS Hellman, Jukka (FI) 2000-05-31 — — EP disclosed
WO-1999009058-A1 ISOLATED OSTEOCALCIN FRAGMENTS HELLMAN JUKKA (FI) 1999-02-25 — — WO disclosed
EP-0060700-B1 ASSAY METHOD AND DEVICE IMMUNO-MYCOLOGICS, INC. (US) 1985-11-21 — — EP disclosed
US-4425438-A Assay method and device IMMUNO-MYCOLOGICS, INC., A CORP. OF OK. 1984-01-10 — — US disclosed
EP-0060700-A1 Assay method and device IMMUNO-MYCOLOGICS, INC. (US) 1982-09-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260086095-A1 METHODS FOR DETECTION OF PROSTATE CANCER, RELATED BIOMARKERS AND KITS FOR DETERMINING THE BIOMARKERS LGALS9, KLK3, SIGLEC9 TDP1 3047/4885MEN1 354/4885ABL1 4795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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