Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 8/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.34 |
| ▸ | SELE | P16581 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853817 | 0.74 | TBXAS1 (0.46) | PTGS1PTGS2ICAM1SELEMEN1 | |
| Oxalic Acid SCHEMBL9853806 | 0.73 | TBXAS1 (0.44) | PTGS1PTGS2ICAM1SELEMAPT | |
| SCHEMBL9853800 | 0.73 | MAPT (0.50) | PTGS1PTGS2KDM4EMEN1ALDH1A1 | |
| SCHEMBL7054411 | 0.69 | TEAD4 (0.47) | PTGS1PTGS2ICAM1SELEGAA | |
| SCHEMBL9853810 | 0.66 | PTGS1 (0.54) | PTGS1PTGS2ICAM1SELEKDM4E | |
| SCHEMBL4374807 | 0.66 | PTGS1 (0.50) | PTGS1PTGS2ICAM1SELEGAA | |
| Hydrochloric Acid SCHEMBL9853816 | 0.65 | PTGS1 (0.49) | PTGS1PTGS2ICAM1SELEGAA | |
| SCHEMBL4370679 | 0.63 | PTGS1 (0.52) | PTGS1PTGS2ICAM1SELEGAA | |
| SCHEMBL4370948 | 0.63 | PTGS1 (0.52) | PTGS1PTGS2ICAM1SELEGAA | |
| SCHEMBL9853814 | 0.62 | KDM4C (0.39) | ICAM1SELEGAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |