Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.38 |
| ▸ | SELE | P16581 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9853806 | 0.96 | TBXAS1 (0.44) | TBXAS1F2CYP4Z1PTGS1PTGS2 | |
| SCHEMBL9853803 | 0.81 | LMNA (0.44) | TBXAS1F2CYP4Z1PTGS1PTGS2 | |
| SCHEMBL9853800 | 0.77 | MAPT (0.50) | PTGS1PTGS2SMN1; SMN2MAPTMEN1 | |
| SCHEMBL7054411 | 0.75 | TEAD4 (0.47) | PTGS1PTGS2ICAM1SELEVCAM1 | |
| SCHEMBL304656 | 0.74 | CYP19A1 (0.63) | TBXAS1CYP4Z1CYP19A1PPIDMAPT | |
| SCHEMBL14676699 | 0.74 | TBXAS1 (0.48) | TBXAS1CYP4Z1SMN1; SMN2LIPEMAOB | |
| SCHEMBL9333883 | 0.74 | MAPT (0.45) | TBXAS1CYP4Z1PTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL9853812 | 0.74 | PTGS1 (0.36) | PTGS1PTGS2ICAM1SELEMAPT | |
| SCHEMBL5894021 | 0.73 | AOC1 (0.47) | TBXAS1SMN1; SMN2PPIDMAPTMEN1 | |
| SCHEMBL68851 | 0.72 | CYP4Z1 (0.62) | TBXAS1CYP4Z1SMN1; SMN2LIPEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | claimed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | claimed |
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |