Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853794 | 0.81 | KDM4E (0.40) | L3MBTL1ALDH1A1TDP1POLBGAA | |
| SCHEMBL14783897 | 0.80 | PDGFRB (0.50) | LMNARAB9AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL9853809 | 0.80 | KMT2A (0.50) | LMNARAB9ACYP1A2MAPTCYP2C9 | |
| SCHEMBL908565 | 0.78 | MEN1 (0.58) | RAB9AMAPTL3MBTL1ALDH1A1PDGFRB | |
| SCHEMBL29923859 | 0.78 | MEN1 (0.58) | RAB9AMAPTL3MBTL1ALDH1A1PDGFRB | |
| SCHEMBL9853813 | 0.77 | KMT2A (0.49) | RAB9ACYP1A2MAPTCYP2C9L3MBTL1 | |
| SCHEMBL9488096 | 0.74 | PTGS1 (0.50) | ALDH1A1 | |
| SCHEMBL9154904 | 0.71 | MAPT (0.54) | LMNARAB9ACYP1A2MAPTCYP2C9 | |
| SCHEMBL9853818 | 0.71 | MAPT (0.47) | LMNARAB9ACYP1A2MAPTCYP2C9 | |
| SCHEMBL2241497 | 0.70 | ALDH1A1 (0.56) | LMNARAB9ACYP1A2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | claimed |
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |