Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4111651 | 0.84 | HPGD (0.60) | MAPTCYP1A2CYP2C9LMNAGAA | |
| SCHEMBL9853813 | 0.76 | KMT2A (0.49) | MAPTCYP1A2CYP2C9GAAKMT2A | |
| SCHEMBL29955136 | 0.75 | ERN1 (0.44) | MAPTGAAKMT2AALDH1A1ERN1 | |
| SCHEMBL10501592 | 0.75 | HPGD (0.50) | MAPTCYP1A2CYP2C9LMNAGAA | |
| SCHEMBL7701305 | 0.75 | ALDH1A1 (0.74) | MAPTCYP1A2CYP2C9LMNAGAA | |
| SCHEMBL9853809 | 0.74 | KMT2A (0.50) | MAPTCYP1A2CYP2C9LMNAGAA | |
| SCHEMBL3838143 | 0.73 | HSPB1 (0.55) | MAPTLMNAGAAKMT2AALDH1A1 | |
| SCHEMBL4434944 | 0.73 | LMNA (0.75) | MAPTCYP1A2CYP2C9LMNAGAA | |
| SCHEMBL9391339 | 0.72 | L3MBTL1 (0.62) | MAPTGAAKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7887959 | 0.72 | HSPB1 (0.47) | MAPTCYP1A2CYP2C9LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | claimed |
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |