SCHEMBL9854439

SCHEMBL9854439

C=CC(=O)OC(C)ONC(=O)c1ccccc1C(=O)NOC(C)OC(=O)C=C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
ALDH1A1 P00352 7/20 0.35
TP53 P04637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.34
CTSD P07339 1/20 0.34
KDM4E B2RXH2 4/20 0.34
HSD17B10 Q99714 3/20 0.33
HTT P42858 2/20 0.33
CFTR P13569 1/20 0.33
PKM P14618 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
HPGD P15428 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3875854 0.84 TAS1R3 (0.36) KMT2AMEN1ALDH1A1HTTPKM
SCHEMBL9854650 0.79 TSHR (0.51) LIG1KMT2AMEN1ALDH1A1CTSD
SCHEMBL301790 0.78 TSHR (0.43) KMT2AALDH1A1L3MBTL1KDM4EHSD17B10
SCHEMBL20481917 0.76 TSHR (0.45) KMT2AALDH1A1KDM4EHSD17B10HTT
SCHEMBL301791 0.73 ALDH1A1 (0.48) KMT2AALDH1A1KDM4EHSD17B10HPGD
SCHEMBL8993412 0.73 LMNA (0.49) KMT2AMEN1ALDH1A1L3MBTL1KDM4E
SCHEMBL17924927 0.73 TSHR (0.39) KMT2AALDH1A1L3MBTL1KDM4EHSD17B10
SCHEMBL1248605 0.72 KDM4E (0.47) KMT2AMEN1ALDH1A1IRAK4KDM4E
SCHEMBL34034 0.71 THRB (0.46) KMT2AMEN1ALDH1A1TP53PKM
SCHEMBL1866176 0.71 TSHR (0.43) KMT2AALDH1A1L3MBTL1IRAK4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0411839-A2 Image forming medium and image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-06 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed
EP-0362827-A1 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-11 EP disclosed
EP-0360014-A1 Photosensitive material and image forming method using same CANON KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed