Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854699 | 0.90 | MTNR1A (0.52) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL9854709 | 0.83 | MTNR1A (0.49) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL19115277 | 0.79 | ALDH1A1 (0.64) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL2464640 | 0.79 | ALDH1A1 (0.64) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL2406505 | 0.74 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AHTTDHODH | |
| SCHEMBL1565743 | 0.74 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AHTTDHODH | |
| SCHEMBL2466967 | 0.71 | MTNR1A (0.52) | MTNR1AMTNR1BALDH1A1HTTDHODH | |
| SCHEMBL9731275 | 0.70 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL24522152 | 0.70 | PIN1 (0.46) | MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL31262384 | 0.69 | PDPK1 (0.44) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420064-A2 | Substituted 2-amidotetralins as melatonin agonists and antagonists | NORTHWESTERN UNIVERSITY (US) | 1991-04-03 | — | — | EP | disclosed |