Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505724 | 0.75 | SMN1; SMN2 (0.36) | MAPTHPGDRAB9A | |
| SCHEMBL122883 | 0.74 | ACACB (0.45) | ACACBMAPTMTNR1AMTNR1BHDAC1 | |
| SCHEMBL1806289 | 0.69 | ACACB (0.43) | ACACBMAPTMTNR1AMTNR1BHDAC1 | |
| SCHEMBL18473337 | 0.69 | ACACB (0.47) | ACACBMAPTHPGD | |
| SCHEMBL12521736 | 0.68 | ALDH1A3 (0.48) | ACACBMAPT | |
| SCHEMBL5684816 | 0.68 | ALDH1A1 (0.41) | ACACBMAPT | |
| SCHEMBL7704361 | 0.68 | MCHR1 (0.37) | HDAC1HDAC2HDAC8 | |
| SCHEMBL8082306 | 0.67 | LMNA (0.52) | ACACBMAPTMTNR1AMTNR1B | |
| SCHEMBL2088447 | 0.67 | ACACB (0.37) | ACACBMAPTMMP2MMP3MMP9 | |
| SCHEMBL8263616 | 0.67 | ACHE (0.42) | ACACBMAPTMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |