SCHEMBL9856229

SCHEMBL9856229

Fc1ccc2c(c1)-c1ccccc1-2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.54
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48
PDK2 Q15119 2/20 0.45
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
PTPN1 P18031 2/20 0.42
HSD11B1 P28845 1/20 0.40
PTPRC P08575 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
NFE2L2 Q16236 2/20 0.38
MEN1 O00255 1/20 0.38
APAF1 O14727 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30997630 0.88 MAPT (0.45) GPR3CYP1A2CYP2A6PDK2L3MBTL1
SCHEMBL563010 0.88 MEN1 (0.55) CYP1A2PTPN1PTPRCL3MBTL1CASP3
SCHEMBL13487417 0.88 PTPRC (0.59) PTPN1PTPRCL3MBTL1MEN1APAF1
SCHEMBL12887889 0.87 CYP1A2 (0.61) GPR3CYP1A2CYP2A6PDK2CA1
SCHEMBL29390818 0.83 PTPRC (0.55) CYP1A2PTPN1PTPRCL3MBTL1CASP3
SCHEMBL13487409 0.83 PTPRC (0.60) PTPN1PTPRCL3MBTL1MEN1APAF1
SCHEMBL181722 0.83 PTPRC (0.55) CYP1A2PTPN1PTPRCL3MBTL1CASP3
SCHEMBL30886642 0.83 PTPRC (0.60) PTPN1PTPRCL3MBTL1MEN1APAF1
SCHEMBL16200908 0.81 ALDH1A1 (0.58) GPR3CYP1A2CYP2A6CA1CA2
SCHEMBL3894758 0.79 MEN1 (0.57) GPR3CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075032-A Electrooptics, switches, displays MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-12-24 US claimed
US-4886620-A Smectic liquid-crystalline phases MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-12-12 US claimed
CN-114262252-A Method for preparing olefin and alkane by catalyzing alkyne with quaternary ammonium salt 云南民族大学 2022-04-01 CN disclosed
US-4886620-A Smectic liquid-crystalline phases MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-12-12 US disclosed